WEEK 1 |     
lecture 1 (Ch1.2-ICB) What is Cystic Fibrosis?
             
|     
lecture 2 (Ch1.2-ICB) What is the Heritable Material (which of the organic/biotic molecules carry genetic info)?
WEEK 2 |     
lecture 1 (Ch4.1-ICB) Let's remember, what is Evolution (can it occur at the molecular & cellular levels)?
             
|     
lecture 2 (Ch4.2-ICB) How did Life begin/evolve on Earth (can abiotic molecules become biotic)?
               
|      
lab week 2 (slides) PCR & Primer Design
WEEK 3 |     
lecture 1 (Ch4.3-ICB & 4.4) How did Life begin/evolve on Earth (can fats become membranes and cells)?
             
|     
lecture 2 (Margulis, Ch8.1 Photosynthesis OSB) How did Life begin/evolve on Earth (what's the origin/evolution of an organelle, e.g. the chloroplast)?
               
|      
lab week 3 (slides) How to write DRAFT1.
WEEK 4 |     
lecture 1 (Ch8.2 Photosynthesis OSB) How did Life begin/evolve on Earth (how does the chloroplast capture light energy)?
             
|     
lecture 2 (Ch8.3 Photosynthesis OSB) How did Life begin/evolve on Earth (how does the chloroplast convert photons into sugar)?
WEEK 5 |     
lecture 1 (Ch11.1-ICB Paraquat?) How did Life begin/evolve on Earth (how did researchers learn how the chloroplast captured light energy)?
             
|     
lecture 2 (Ch11.2-ICB Brazil?) How did Life begin/evolve on Earth (how did researchers learn how the chloroplast convert photons into sugar)?
WEEK 6 |     
[ exam day ]
             
|     
lecture 2 (Rowe et al NEJM 2005) Cystic Fibrosis: Mechanisms of Disease (how does a broken CFTR gene cause the disease?)
             
|     
lab week 6 (slides) TopTen Tips for DRAFT2 (remember read any/all instructions four times for 4.0)
WEEK 7 |     
lecture 1 (Ch5.1-ICB) Cystic Fibrosis: How do genetic diseases arise (is the CFTR gene mutated from radiation exposure, or UV light, or what)?
             
|     
lecture 2 (Ch4.3 Cell Structure OSB) Cystic Fibrosis: How do cells work when healthy (how are prokaryotic and eukaryotic cells different)?
               
|      
lab week 7 (slides) Gel Troubleshooting.
WEEK 8 |     
lecture 1 (Ch4.4 Cell Structure OSB) Cystic Fibrosis: How do cells make new CFTRs when healthy (DNA becomes RNA becomes proteins but how/where)?
             
|     
lecture 2 (Ch8.2-ICB FRAP!) Cystic Fibrosis: How do cell membranes behave when healthy (do CFTRs flop around inside the membrane)?
WEEK 9 |     
lecture 1 (Ch5.2 Membranes OSB) Cystic Fibrosis: How do cell membranes behave when healthy (why do we need CFTRs to carry ions)?
             
|     
lecture 2 (Ch5.3 Membranes OSB) Cystic Fibrosis: What are ion gradients (is the CFTR a carrier or channel or pump)?
WEEK 10 |     
lecture 1 (Ch39.1 Respiratory System OSB) Cystic Fibrosis: How do lungs work (and how does oxygen travel in blood)?
               
|     
[ exam day ]     
WEEK 11 |     
lecture 1 (Polonsky et al NEJM 2012) Diabetes: The Past 200 Years (what causes the disease, how to cure treat it?)
               
|     
lecture 2 (Ch23.1-ICB digestion) Diabetes: When we eat, how does the pancreas normally work (how does it create new insulins)?
WEEK 12 |     
lecture 1 (Ch1.4-ICB DNA+ELSI) Diabetes: What's the structure of DNA (what does insulin DNA and RNA look like)?
               
|     
lecture 2 (Ch15.3, 15.5 Genes OSB) Diabetes: Gene transcription and translation into proteins (how does insulin DNA become RNA, and RNA become proteins)?
WEEK 13 |     
lecture 1 (Ch2.1-ICB how DNA communicates) Diabetes: Transcription and translation (how did researchers learn this)?
               
|     
lecture 2 (Ch2.4-ICB how DNA communicates) Diabetes: DNA, RNA, protein sequences of insulin (how do you use NCBI, OMIM, ORF etc)?
WEEK 14 |     
lecture 1 (Ch10.4-ICB Make ATP) Diabetes: After insulin works, food molecules can enter and... (how does food then become ATP molecules)?
               
|     
lecture 2 (Ch10.4+ELSI) Diabetes: After insulin works, food molecules can enter and... (the other respiration)?