Student Resources
Introductory Cell & Molecular Biology (LB145-BioCore Spring 2025)
Lyman Briggs College, Michigan State University


WEEK 1 |      lecture 1 (Ch1.2-ICB) What is Cystic Fibrosis?
              |      lecture 2 (Ch1.2-ICB) What is the Heritable Material (which of the organic/biotic molecules carry genetic info)?



WEEK 2 |      lecture 1 (Ch4.1-ICB) Let's remember, what is Evolution (can it occur at the molecular & cellular levels)?
              |      lecture 2 (Ch4.2-ICB) How did Life begin/evolve on Earth (can abiotic molecules become biotic)?

                |       lab week 2 (slides) PCR & Primer Design



WEEK 3 |      lecture 1 (Ch4.3-ICB & 4.4) How did Life begin/evolve on Earth (can fats become membranes and cells)?
              |      lecture 2 (Margulis, Ch8.1 Photosynthesis OSB) How did Life begin/evolve on Earth (what's the origin/evolution of an organelle, e.g. the chloroplast)?

                |       lab week 3 (slides) How to write DRAFT1.



WEEK 4 |      lecture 1 (Ch8.2 Photosynthesis OSB) How did Life begin/evolve on Earth (how does the chloroplast capture light energy)?
              |      lecture 2 (Ch8.3 Photosynthesis OSB) How did Life begin/evolve on Earth (how does the chloroplast convert photons into sugar)?



WEEK 5 |      lecture 1 (Ch11.1-ICB Paraquat?) How did Life begin/evolve on Earth (how did researchers learn how the chloroplast captured light energy)?
              |      lecture 2 (Ch11.2-ICB Brazil?) How did Life begin/evolve on Earth (how did researchers learn how the chloroplast convert photons into sugar)?



WEEK 6 |      [ exam day ]
              |      lecture 2 (Rowe et al NEJM 2005) Cystic Fibrosis: Mechanisms of Disease (how does a broken CFTR gene cause the disease?)
              |      lab week 6 (slides) TopTen Tips for DRAFT2 (remember read any/all instructions four times for 4.0)



WEEK 7 |      lecture 1 (Ch5.1-ICB) Cystic Fibrosis: How do genetic diseases arise (is the CFTR gene mutated from radiation exposure, or UV light, or what)?
              |      lecture 2 (Ch4.3 Cell Structure OSB) Cystic Fibrosis: How do cells work when healthy (how are prokaryotic and eukaryotic cells different)?

                |       lab week 7 (slides) Gel Troubleshooting.



WEEK 8 |      lecture 1 (Ch4.4 Cell Structure OSB) Cystic Fibrosis: How do cells make new CFTRs when healthy (DNA becomes RNA becomes proteins but how/where)?
              |      lecture 2 (Ch8.2-ICB FRAP!) Cystic Fibrosis: How do cell membranes behave when healthy (do CFTRs flop around inside the membrane)?



WEEK 9 |      lecture 1 (Ch5.2 Membranes OSB) Cystic Fibrosis: How do cell membranes behave when healthy (why do we need CFTRs to carry ions)?
              |      lecture 2 (Ch5.3 Membranes OSB) Cystic Fibrosis: What are ion gradients (is the CFTR a carrier or channel or pump)?



WEEK 10 |      lecture 1 (Ch39.1 Respiratory System OSB) Cystic Fibrosis: How do lungs work (and how does oxygen travel in blood)?
                |      [ exam day ]     



WEEK 11 |      lecture 1 (Polonsky et al NEJM 2012) Diabetes: The Past 200 Years (what causes the disease, how to cure treat it?)
                |      lecture 2 (Ch23.1-ICB digestion) Diabetes: When we eat, how does the pancreas normally work (how does it create new insulins)?



WEEK 12 |      lecture 1 (Ch1.4-ICB DNA+ELSI) Diabetes: What's the structure of DNA (what does insulin DNA and RNA look like)?
                |      lecture 2 (Ch15.3, 15.5 Genes OSB) Diabetes: Gene transcription and translation into proteins (how does insulin DNA become RNA, and RNA become proteins)?



WEEK 13 |      lecture 1 (Ch2.1-ICB how DNA communicates) Diabetes: Transcription and translation (how did researchers learn this)?
                |      lecture 2 (Ch2.4-ICB how DNA communicates) Diabetes: DNA, RNA, protein sequences of insulin (how do you use NCBI, OMIM, ORF etc)?



WEEK 14 |      lecture 1 (Ch10.4-ICB Make ATP) Diabetes: After insulin works, food molecules can enter and... (how does food then become ATP molecules)?
                |      lecture 2 (Ch10.4+ELSI) Diabetes: After insulin works, food molecules can enter and... (the other respiration)?







Contact me at:  luckie@msu.edu